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Zyban (Bupropion)

Generic Name: Zyban
Brand name: Bupropion

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Uses

Zyban is used to help you quit smoking.

How To Use?

Swallow Zyban whole. Do not crush or chew them or the sustained activity of the drug will be destroyed and the chances of side effects occurring may be increased. Take as directed, usually twice daily for 7 to 12 weeks. Do not take more or less medication than prescribed. Since Zyban can cause sleeplessness at first, it is best not to take near bedtime. Taking more than the recommended dose of bupropion will increase your risk of having a seizure. It is advised to continue smoking for the first week after starting Zyban, until it reaches higher levels in your blood. Do not smoke if using any nicotine products with Zyban. Too much nicotine can cause serious side effects. Do not stop taking Zyban without notifying your doctor.

Side Effects

• If you experience any of the following uncommon but serious side effects, stop taking bupropion and seek emergency medical attention or contact your doctor immediately:
    · an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
    · seizures; or
    · fast or irregular heartbeats.
• Other, less serious side effects may be more likely to occur. Continue to take bupropion and talk to your doctor if you experience
    · headache;
    · insomnia;
    · dry mouth;
    · tremors, restlessness, agitation, or anxiety;
    · dizziness or drowsiness;
    · sweating;
    · skin rash;
    · ringing in the ears;
    · flulike symptoms such as aching muscles, fatigue, and discomfort;
    · frequent urination; or
    · weight loss or gain.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Precautions

Tell your doctor your medical history, especially of: seizures, head injury, brain tumor, heart disease, liver problems, kidney problems, eating disorder, any mental conditions, diabetes, alcohol dependence, any allergies. Because of the possibility Zyban will make you dizzy and affect coordination, do not drive or operate machinery until you get used to the drug's effects. Limit or avoid consumption of alcoholic beverages; alcohol can increase your risk of seizures. Chronic alcohol users who suddenly stop the intake of alcohol while taking bupropion may increase the risk of having seizures. Suddenly stopping certain tranquilizers (e.g., diazepam, chlordiazepoxide) is not recommended because doing so may increase the risk of having seizures. Elderly patients may be more sensitive to the effects of Zyban. Tell your doctor if you are pregnant or plan to become pregnant before taking Zyban. Zyban passes into breast milk. Because of the potential risk to the infant, breast-feeding while using Zyban is not recommended. Consult your doctor before breast-feeding.

Drug Interactions

Before taking Zyban tell your doctor of all nonprescription and prescription medications you may use especially: MAO inhibitors (e.g., isocarboxazid, phenelzine, tranylcypromine, pargyline, selegiline, linezolid, furazolidone), levodopa, ritonavir, corticosteroids (e.g. prednisone), sedatives, adrenaline-like stimulants (e.g., ephedrine), products containing nicotine (e.g., patches or gum). Also report use of drugs which might increase seizure risk (decrease seizure threshold) such as: phenothiazines (e.g., chlorpromazine), tricyclic antidepressants (e.g., amitriptyline), isoniazid (INH), theophylline. Excess caffeine intake can increase the chance of seizures with Zyban. Check all nonprescription/prescription drug labels for caffeine. Consult your doctor or pharmacist. A certain product used to help quit smoking contains Zyban. Do not take that product while using this one. Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include blurred vision, lightheadedness, confusion, nausea, and seizures.

Notes

Do not allow anyone else to take Zyban.

Missed Dose

Take any missed dose as soon as possible but not if it is within 8 hours of the next dose. If it is time for the next dose, skip the missed dose and resume your regular schedule. Do not "double-up" the dose.

Storage

Store at room temperature and keep away from moisture and sunlight. Do not store in the bathroom.
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