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Generic Name: Itraconazole
Brand name: Sporanox
 
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Uses
Sporanox is a drug used in the treatment of fungal infections, such as aspergillosis, blastomycosis, histoplasmosis, and fungal infection localized to the toenails and fingernails (onychomycosis).
How To Take This Medication?
Take Sporanox exactly as prescribed. To make sure the capsules are properly absorbed, you should take them after a full meal; the oral solution should be taken without food. A cola drink can help some people absorb the capsules better. Continue taking Sporanox until all the medication is gone. Do not take antacids within 1 hour before or 2 hours after taking Sporanox.
Swish the oral solution, 10 milliliters at a time, in your mouth for a few seconds before swallowing it.
Mouth and throat candidiasis should clear up in several days.
The oral solution and capsules cannot be used interchangeably.
Side Effects
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Sporanox.
- More common side effects may include:
Anxiety, bursitis, diarrhea, fatigue, fever, gas, headache, high blood pressure, indigestion, injury, muscle pain, nasal and sinus inflammation, nausea, pain, rash, respiratory infection, swelling due to water retention, urinary infection, vomiting
- Less common side effects may include:
Abdominal pain, abnormal dreams, allergic reaction, decreased sexual drive, dizziness, extreme sleepiness, feeling of general discomfort, gum inflammation, hives, increased appetite, inflamed stomach and intestines, itching, loss of appetite, reproductive disorders such as male impotence, sleepiness, sore throat, tremor, weakness
- Rare side effects may include:
Blood abnormalities, congestive heart failure, constipation, depression, fluid in the lungs, hair loss, hepatitis, high triglyceride levels, liver failure, male breast development, male breast pain, menstrual disorders, nerve disorders, ringing in the ears, severe allergic reaction, skin peeling, sleeplessness
- Additional side effects that may be seen with the oral solution are:
Back pain, blood in the urine, breathing difficulty, chest pain, cough, dehydration, difficulty swallowing, hemorrhoids, hot flushes, impaired speech, inflamed mouth, insomnia, pneumonia, shivering, sweating, vision problems, weight loss
People being treated for onychomycosis may experience stomach and intestinal disorders or rash, or, less commonly, headache, light-headedness upon standing up, low blood pressure, muscle pain, a sick feeling, or vertigo.
Precautions
In rare cases, Sporanox has been known to cause liver failure and even death. If you have liver disease, or if you take Sporanox continuously for more than a month, your doctor should monitor your liver function periodically. If you develop such symptoms of liver disease as unusual fatigue, loss of appetite, nausea, vomiting, jaundice, dark urine, or pale stool, stop taking Sporanox and contact your doctor immediately.
People with cardiac problems such as congestive heart failure should avoid Sporanox unless the benefit clearly outweighs the danger. In fact, anyone who is even at risk of heart failure should use Sporanox with caution. Risk factors include heart and lung disorders and kidney failure. If you experience swelling--especially in the feet and ankles--or difficulty breathing while taking Sporanox, stop taking this medication and contact your doctor immediately.
If you develop any nerve disorders while taking Sporanox, see your doctor. Treatment will probably need to be discontinued.
Drug Interactions
Liver tests are monitored periodically in most patients, especially if receiving continuous treatment for more than one month. Sporanox is used with caution in any patient with liver dysfunction.
The use of Sporanox in children is not recommended because it's safety has not been established.
Itraconazole is not used with following medications: terfenadine (Seldane), cisapride (Propulsid), astemizole (Hismanal), triazolam (Halcion) or midazolam (Versed).
Overdose
Any drug taken in excess can have dangerous consequences. If you suspect an overdose, seek emergency medical treatment immediately.
Missed Dose
Take the forgotten dose as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to your regular schedule.
Storage
Store Sporanox at room temperature. Protect the capsules from light and moisture. Do not freeze the oral solution.
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