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Generic Name: Sibutramine
Brand name: Meridia
   
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Uses
Meridia is used to reduce excess body weight (obesity).
How To Use
Take by mouth exactly as directed by your doctor, usually once daily. The full effect on weight may require four to six weeks. Do not increase your dose, take it more frequently or use it for a longer period of time than prescribed because Meridia can be habit-forming. Also, if used for a longer period of time, do not suddenly stop using Meridia without your doctor's approval. Over time, Meridia may not work as well as it did at the beginning. Consult your doctor if weight increases.
Side Effects
If you experience any of the following serious side effects, stop taking Meridia and seek emergency medical attention or contact your doctor immediately:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- an irregular heartbeat;
- high blood pressure (severe headache, blurred vision); or
- seizures.
Other, less serious side effects may be more likely to occur. Continue to take Meridia and talk to your doctor if you experience
- restlessness or tremor,
- nervousness or anxiety,
- mild headache or dizziness,
- insomnia,
- dry mouth or an unpleasant taste in your mouth, or
- constipation.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Precautions
Before using Meridia, tell your doctor your entire medical history, including: any allergies (especially drug allergies), liver or kidney disease, high blood pressure, heart disease, history of stroke or seizures, certain eating disorders (e.g., anorexia nervosa), glaucoma (narrow angle), history of gallstones. Limit alcohol intake, as it may worsen certain side effects of Meridia. Since Meridia may cause dizziness or fatigue, use extreme caution if operating machinery or performing hazardous tasks (e.g., driving). It is recommended that women of child-bearing age should use effective birth control while taking Meridia. Meridia is not recommended for use during pregnancy. Consult your doctor before using Meridia. It is not known whether Meridia is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using Meridia is not recommended. Consult your doctor before breast-feeding. Elderly patients may be more sensitive to the effects of Meridia. Use cautiously.
Drug Interactions
Tell your doctor of all nonprescription and prescription drugs you may use, especially: other weight reducing agents (e.g., diethylpropion), drugs that can raise blood pressure such as decongestants (e.g., pseudoephedrine, phenylpropanolamine), cough suppressants (e.g., dextromethorphan), antidepressants (e.g., nefazodone, fluoxetine, paroxetine, sertraline, fluvoxamine, venlafaxine), lithium, psychiatric medications (e.g., MAO inhibitors such as selegiline, moclobemide, furazolidone, phenelzine, tranylcypromine, procarbazine, linezolid), drugs for migraines (e.g., dihydroergotamine, sumatriptan), tryptophan, certain narcotic pain relievers (e.g., meperidine, pentazocine, fentanyl), ketoconazole, erythromycin, high blood pressure medicine. Tell your doctor if you take drugs that cause drowsiness: medicine for sleep, sedatives, tranquilizers, anti-anxiety drugs (e.g., diazepam), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., phenothiazines or tricyclics), anti- seizure drugs (e.g., carbamazepine), muscle relaxants, antihistamines that cause drowsiness (e.g., diphenhydramine). Antihistamines and decongestants may be found in many nonprescription drugs for cough and cold. Consult your pharmacist. MAO inhibitors (see above) and Meridia should not be taken together. If an MAO inhibitor or Meridia is stopped, wait 2 weeks before starting the other drug. Do not start or stop any medicine without doctor or pharmacist approval.
Overdose
If overdose of Meridia is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include fast heartbeat.
Notes
Do not share Meridia with others. Meridia should be used in addition to a reduced calorie diet. Blood pressure and pulse may be measured and laboratory tests performed to monitor side effects.
Missed Dose
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of Meridia.
StorageStore at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture.
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