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Generic Name: Actos
Brand name: PIOGLITAZONE
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Uses
Actos is an anti-diabetic drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes (non-insulin-dependent diabetes). Actos works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Effectively controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness, and circulation problems, as well as sexual function problems (impotence).
How To Use
Take Actos tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water with meals. Take your doses at the same time each day; do not take more often than directed.
Side Effects
Sore throat, muscle pain, or tooth problems may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Tell your doctor immediately if any of these unlikely but serious side effects occur: swelling, unexplained rapid weight gain, trouble breathing, unusual fatigue, fast/pounding heartbeat, changes in menstrual cycles.
Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: dark urine, yellowing of eyes/skin, persistent nausea/vomiting, stomach/abdominal pain.
Actos usually does not cause low blood sugar (hypoglycemia), but this effect may occur if you do not consume enough calories (from food, juices, fruit, etc.). The symptoms include chills, cold sweat, dizziness, drowsiness, shaking, rapid heart rate, weakness, headache, fainting, tingling of the hands or feet, or hunger. It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you are in a situation where you don't have these reliable forms of glucose, eat a quick source of sugar such as table sugar, honey, or candy, or drink a glass of orange juice or non-diet soda to quickly raise your blood sugar level. Tell your doctor immediately about the reaction. To help prevent hypoglycemia, eat meals on a regular schedule and do not skip meals.
Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, or fruity breath odor. If these symptoms occur, tell your doctor immediately. Your medication dosage may need to be increased.
A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.
Precautions
Visit your prescriber or health care professional for regular checks on your progress. Learn how to monitor blood or urine sugar and urine ketones regularly. Check with your prescriber or health care professional if your blood sugar is high, you may need a change of dose of actos. Do not skip meals. If you are exercising much more than usual you may need extra snacks to avoid side effects caused by low blood sugar. If you have mild symptoms of low blood sugar, eat or drink something containing sugar at once and contact your prescriber or health care professional. It is wise to check your blood sugar to confirm that it is low. It is important to recognize your own symptoms of low blood sugar so that you can treat them quickly. Make sure family members know that you can choke if you eat or drink when you have serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.
Your health care professional will have to check blood tests regularly to assess the effect of this medication on your liver. Actos may rarely cause changes in some of these measurements.
If you are going to have surgery, tell your prescriber or health care professional that you are taking actos.
Wear a medical identification bracelet or chain to say you have diabetes, and carry a card that lists all your medications.
Drug Interactions
Before using Actos, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: other anti-diabetic medications (e.g., insulin, metformin, or sulfonylureas such as glyburide), herbal/natural products (e.g., fenugreek, ginseng, gymnema).
Actos may decrease the effectiveness of birth control pills. This can result in pregnancy. You may need to use an additional form of reliable birth control while using Actos. Consult your doctor or pharmacist for details.
Do not start or stop any medicine without doctor or pharmacist approval.
Notes
Prescriber needs to know if you have any of these conditions: heart problems; kidney or liver problems; swelling of the arms, legs, or feet; an unusual or allergic reaction to Actos, other medicines, foods, dyes, or preservatives; pregnant or trying to get pregnant; breast-feeding.
Missed Dose
If you miss a dose, take it with the next meal. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Storage
Keep out of the reach of children in a container that small children cannot open. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed and protect from moisture and humidity. Throw away any unused medicine after the expiration date.
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